Patients who suffer from fibromyalgia often have difficulty in finding an effective treatment that addresses their pain and allows them to remain active. These top three treatments of Lyrica, Cymbalta, and Savella have all been approved by the FDA for the treatment of the condition. In many cases, patients work with their physicians in order to find a customized treatment plan that effectively treats their symptoms as taking one drug is often not enough for them to lead full and active lives. Many drug companies are developing more advanced treatment drugs but they are not yet approved. In the meantime, speak with your doctor about the benefits of these top 3 FDA-approved drugs for the treatment of your fibromyalgia.


This is the very first drug that was approved for the treatment of fibromyalgia and remains the most commonly prescribed. The benefits of Lyrica include more restful sleep, a decrease in pain, and a noticeably less amount of fatigue. If you suffer from FMS and want to resume a more active life, it may be time to discuss Lyrica with your physician. The drug affects the neurotransmitters in the brain lessening the amount of pain that the body feels thereby increasing the patient’s overall sense of well-being. Manufactured by Pizer, this medication is also approved for the treatment of pain caused by diabetic neuropathy.


Cymbalta is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI) and is effective in producing more serotonin and norepinephrine as many fibromyalgia sufferers are deficient in these two substances. The decrease in the reuptake allows these neurotransmitters to be absorbed into the brain and bloodstream more readily thus decreasing the pain that the patient experiences. Patients that also suffer from depression due to the symptoms of FMS have also experienced relief from the symptoms of that condition as well.


This drug was originally created for the treatment of depression, similar to Cymbalta. It is an effective treatment option for sufferers of fibromyalgia who also experience depression. The main innovation with this medication is that it boosts norepinephrine levels more than the level of serotonin. This approach has proven effective for many people who suffer from fibromyalgia and whose symptoms have caused them to lead a much less active and full life than they had done before the onset of their condition. Another attractive feature of this medication is its low incidence of side effects and the fact that the majority of side effects that are experienced are mild to moderate.